If I set a breakpoint in the ValueChanged event of a DateTimePicker (C# or VB.net) I get the error "vshost-clr2.exe is not responding". I can set break into other event handlers such as click without any issues. This is from a Windows Forms application and can be reproduced using C# or VB.net
Using VS2013 update 5 CTP with .net 4.5 project(s).
I've also tried this on another PC running Windows 8.1 and the base release of VS2013, results are even more catastrophic - hard reset of laptop is the only way to recover.
More info can be found here: